Atara Biotherapeutics, Inc. Sr. Research Associate - Process Sciences in Denver, Colorado
This Sr. Research Associate position will work with the Process Sciences teams to develop and characterize cell therapy manufacturing processes and products, focusing on allogeneic CAR-T cells.
The Sr. Research Associate will be responsible for contributing to the process development of allogeneic CAR-T cells to enable clinical trials. You will be responsible for cell processing, process engineering scale-up/scale-down, bioreactor process parameters, assessment of novel technologies, cryopreservation, and equipment maintenance. You will be expected to perform experiments, organize, and carefully document results, analyze and interoperate results, and communicate findings.
Reports to: Sr. Scientist, Process Development
Location: This role is available for hire in either Aurora, CO or Thousand Oaks, CA
Contribute to the development of manufacturing processes for allogeneic CAR-T cells using suspension bioreactor technologies
Executes studies to facilitate development of allogeneic CAR-T processes and enabling clinical trials.
Executes process development studies to develop a thorough understanding of operating and performance parameters (Design space).
Executes studies to develop process to obtain optimal cell characteristics to establish allogeneic CAR-T platform
Perform problem solving in the areas of bio-manufacturing and process engineering scale-up
Optimize bioreactor parameters and evaluate alternative technologies
Performs multiplexed cell-based assays (killing assays, mixed lymphocyte reactions, proliferation assays, etc.) for process assessment and product characterization.
Role model for Atara’s Values of patients first, innovation teamwork, community and mindset.
Education and Experience:
BS in Immunology, biological or engineering science with 2+ years of related industry experience
Experience with operating and optimizing bioreactor cultures, preferably in a cell therapy application
Knowledge and experience in mammalian cell culture / biotechnology related development (aseptic operations, cell biology, biochemistry, bioreactor operations)
Experience with the generation and evaluation of human CAR-T therapies; Industry experience in adoptive T cell, CAR-T, or TCR therapeutics preferred.
Familiarity with development and /or commercialization of cell-based therapeutics
Comfortable in a fast-paced small company environment with minimal direction and able to adjust workload based upon changing priorities
We launched Atara Biotherapeutics in August 2012 to help patients with serious diseases and few therapeutic options. We’re named after Atara Ciechanover who suffered from cancer before passing away. We are considered a leading off-the-shelf T-cell immunotherapy company (Nasdaq ATRA) developing novel treatments for patients with cancer, autoimmune and viral diseases.
We’re proud of our team of 350+ Atarians co-located by design in South San Francisco (corporate headquarters) and Southern California (R&D and manufacturing headquarters in the northwest Los Angeles area) with a newly-established European headquarters in Zug, Switzerland. Atara also has a R&D site in the Denver, Colorado area and an office in New York City. Our Southern California hub is anchored by a new 90,000 sq. ft., state-of-the-art Atara T-Cell Operations and Manufacturing (ATOM) facility in Thousand Oaks, California.
Our mission – “Transform the lives of patients with serious medical conditions through pioneering science, teamwork, and a commitment to excellence.”
Our vision - “T-Cell Immunotherapy for every patient, any time.”
Visit www.atarabio.com to learn more.
Atara Bio is an equal opportunity employer and makes employment decisions on the basis of merit and other lawful factors. In accordance with applicable law, the Company prohibits discrimination based on race, color, religion, creed, sex, gender (including pregnancy, childbirth or medical condition related to pregnancy or childbirth), gender identity, expression or dysphoria, marital status, age, national origin or ancestry, physical or mental disability, medical condition, genetic information, veteran status, caregiver status, sexual orientation, transgender status or any other classification protected by federal, state or local laws or because of the individual’s association with a member of a protected group or connection to an organization or group related to a protected group.
We comply with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Atara Bio in the United States.
Official Title: Sr. Research Associate - Process Sciences
Job ID: 2020-1403
External Company Name: Atara Biotherapeutics, Inc.
External Company URL: https://www.atarabio.com/